By HEIDELBERG UNIVERSITY JULY 20, 2022
The researchers are currently trying to find out what causes this improved drought resistance.
目前,此些研究人正找出,什致改善的抗旱性。
Researchers from Heidelberg University uncover a crucial protein in a mechanism that regulates the life of proteins
自德海德堡大的研究人,在蛋白命的制中,了一蛋白。
Proteins serve a variety of purposes in plants in addition to being the fundamental building blocks of life. More than 20 billion protein molecules make up a typical plant cell, helping to stabilize its structure and sustain cellular metabolism.
除了是生命的基材之外,蛋白在植物中,也具有多用途。超2百蛋白分子成一,有助於定植物及持胞代的典型植物胞。
Researchers at Heidelberg University’s Centre for Organismal Studies have shed light on a biological process that increases the life of plant proteins. They have now discovered a crucial protein, called N-terminal acetylation, that controls this mechanism. The study’s findings were published in the journals Molecular Plant and Science Advances.
海德堡大生物研究中心的研究人已明一,有增加植物蛋白命的生物程。目前,他已一,控制此制,被N末端乙酰化的性蛋白。研究的果,表於《分子植物》及《科展》期刊。
N-terminal acetylation is a chemical marker that develops during the production of proteins. Plants do this by affixing an acetic acid residue to the beginning of the protein. The majority of proteins are shielded from degradation by the so-called proteasome, a form of molecular shredder, by this acetic acid residue.
N末端乙酰化是一,在蛋白生程中,生的化。植物藉由在蛋白的早期段,添加一乙酸基,生此化。大多蛋白由所的蛋白酶(一分子粉碎),透乙酸基,被保免於降解。
The important protein that has now been found, according to the Heidelberg researchers led by Professor Dr. Rüdiger Hell and Dr. Markus Wirtz, is known as the Huntingtin Yeast Interactor Protein K (HYPK). It promotes N-terminal acetylation, extending the lifespan of plant proteins—important for, among other things, adapting to environmental circumstances.
根由教授Rüdiger Hell博士及Markus Wirtz博士之海德堡大研究人的法,目前已被的重要蛋白,被通亨廷酵母相互作用物蛋白K (HYPK)。它促N末端乙酰化,延植物蛋白命。其他事中,於境的多,也很重要。
1. 比供充足(照)及受乾旱力之野生型(WT)植物HYPK突的表型表。乾旱力被施加到,大5的植物24天。比例尺 = 2厘米。 (援用自原文)
The Heidelberg team used thale cress (Arabidopsis thaliana) to investigate the regulation properties of the HYPK protein. Due to its well-studied genome, the plant from the family Brassicaceae is a popular model organism.
海德堡大使用了阿拉伯芥(Arabidopsis thaliana,又名南芥),研究HYPK蛋白的多特性。由於其充分被研究的基因,十字花科植物是一普遍的模型生物。
Reearch on genetically altered plants has shown that the life of proteins is reduced when the HYPK protein is absent and N-terminal acetylation does not take place. At the same time, the plant’s resistance to ongoing drought rises. Rüdiger Hell states, “Our current research is directed to finding out how this improved drought resistance comes about.”
有改之植物的研究已,HYPK蛋白不存在,且生N-末端乙酰化,蛋白的命少。在此同,植物提高了,於持乾旱的抵抗力。Rüdiger Hell述:「目前,我的研究是指向,找出改善的抗旱性,如何生。」
In cooperation with researchers from the Chinese Academy of Sciences in Beijing (China) under the direction of Professor Dr. Yonghong Wang, the Heidelberg scientists also discovered that HYPK performs its regulatory function not only in thale cress but also in rice, one of the world’s oldest crops. The protein is also found in humans and in many fungi.
在自中北京中科院,由教授Yonghong Wang博士指之研究人的合作下,些海德堡大的科家也,HYPK蛋白不在阿拉伯芥中,而且在水稻(世界上最古老的作物之一)中,生其功能。
“The mechanism involved in acetylation and its control by HYPK appears to be one that developed billions of years ago and has been retained in very different organisms to this day,” explains Markus Wirtz.
The studies are being funded by the German Research Foundation.
Markus Wirtz解:「在乙酰化中被涉及,其由HYPK蛋白控制的制,然是一十年前所演化,且至今在非常不同的生物中,一直被保有的制。」些研究是由德研究基金所助。
址:https://scitechdaily.com/scientists-have-created-genetically-modified-drought-resistant-plants/
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